A fifth straight win for the Spiders give them their best record through 26 games since 2010-11.
The Spiders' need to dust themselves off quickly as the next game is against local rival VCU.
La Salle had no answers to Richmond's defense but showed brief signs of life in the second half.
A poor second half and missed three-pointers lead to Spider defeat.
Spider nabbed their seventh straight victory at home on Saturday night.
The Spiders easily take care of the visitors from South Alabama with a strong second half.
The University of Richmond extended their unbeaten streak to four with a win over McNeese State on Friday night.
The Cal State-Northridge Matadors were run over by a Spider shaped bull on Sunday.